Shugoshins: Tension-Sensitive Pericentromeric Adaptors Safeguarding Chromosome Segregation
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Shugoshins: Tension-Sensitive Pericentromeric Adaptors Safeguarding Chromosome Segregation
The shugoshin/Mei-S332 family are proteins that associate with the chromosomal region surrounding the centromere (the pericentromere) and that play multiple and distinct roles in ensuring the accuracy of chromosome segregation during both mitosis and meiosis. The underlying role of shugoshins appears to be to serve as pericentromeric adaptor proteins that recruit several different effectors to ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2015
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.01176-14